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| Third Basemen Career Runs Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Runs | PA | Years | Single Season Leaderboard |
| 1. | Joseph Rosado | 452 | 2667 | 1947-1950 | |
| 2. | Jacky Baeza | 443 | 2690 | 1947-1950 | |
| 3. | Jose Sanchez | 371 | 2584 | 1947-1950 | |
| 4. | Luis Rosenblatt | 368 | 2677 | 1947-1950 | |
| 5. | Sean Brinkerhoff | 358 | 2687 | 1947-1950 | |
| 6. | Jose Carbonell | 354 | 2610 | 1947-1950 | |
| Eric Salas | 354 | 2584 | 1947-1950 | ||
| 8. | Orlando Marquez | 332 | 2051 | 1948-1950 | |
| 9. | James Ethier | 308 | 2416 | 1947-1950 | |
| 10. | Mark Browne | 300 | 2577 | 1947-1950 | |
| 11. | Michael Duncanson | 299 | 2402 | 1947-1950 | |
| 12. | Max Acuņa | 268 | 2480 | 1947-1950 | |
| 13. | Dave Romeo | 243 | 1844 | 1947-1949 | |
| 14. | Richard Raynor | 221 | 2254 | 1947-1950 | |
| 15. | Lloyd Wall | 219 | 2072 | 1947-1950 | |
| 16. | Bobby Zendejas | 190 | 1592 | 1947-1949 | |
| 17. | John Lucas | 165 | 1665 | 1947-1950 | |
| 18. | Michael Longoria | 138 | 1003 | 1948-1950 | |
| 19. | Craig Calvin | 127 | 1291 | 1947-1950 | |
| 20. | Brian Thompson | 126 | 1410 | 1947-1949 | |
| 21. | Leonard Ware | 114 | 709 | 1948-1950 | |
| 22. | Christopher Rohde | 112 | 902 | 1948-1950 | |
| David Shoaf | 112 | 983 | 1947-1948 | ||
| 24. | Michael Fraser | 109 | 1415 | 1947-1949 | |
| 25. | Paul South | 99 | 1143 | 1949-1950 | |
| 26. | Paul Oberry | 94 | 834 | 1947-1949 | |
| 27. | George Font | 89 | 962 | 1948-1950 | |
| 28. | John Hite | 88 | 570 | 1947-1950 | |
| 29. | Elmer Stromain | 86 | 667 | 1949-1950 | |
| 30. | Bradley Forgey | 84 | 821 | 1947-1948 | |
| 31. | David Bachand | 78 | 911 | 1948-1950 | |
| 32. | Alonso Gonzalez | 75 | 609 | 1947-1949 | |
| 33. | Bob Yingling | 70 | 604 | 1947-1948 | |
| 34. | Arthur Sims | 56 | 363 | 1950-1950 | |
| 35. | Robert Braatz | 54 | 469 | 1947-1950 | |
| 36. | Gilbert McCraney | 52 | 514 | 1947-1949 | |
| 37. | Dusty Brown | 42 | 465 | 1947-1950 | |
| 38. | Ronald Gildersleeve | 40 | 326 | 1950-1950 | |
| 39. | Ray Johnson | 39 | 370 | 1947-1948 | |
| 40. | Roderick Petrie | 35 | 412 | 1947-1950 | |
| 41. | Bill Parmelee | 32 | 250 | 1947-1949 | |
| 42. | Brian Teets | 31 | 237 | 1947-1948 | |
| 43. | Kenneth Kendall | 30 | 279 | 1948-1949 | |
| 44. | Douglas Conard | 26 | 138 | 1947-1948 | |
| 45. | Robert Trader | 24 | 214 | 1947-1947 | |
| 46. | John Peterson | 21 | 109 | 1950-1950 | |
| 47. | Wade Giuliani | 18 | 204 | 1947-1950 | |
| 48. | Benjamin Marrufo | 14 | 132 | 1950-1950 | |
| 49. | Floyd Mackay | 12 | 132 | 1947-1950 | |
| Gerald Reif | 12 | 77 | 1950-1950 | ||
| 51. | Jose Naranjo | 11 | 126 | 1950-1950 | |
| 52. | Josias Grillo | 10 | 84 | 1947-1947 | |
| 53. | Enrique Belmonte | 7 | 76 | 1950-1950 | |
| Wilfredo Acosta | 7 | 63 | 1949-1950 | ||
| 55. | Jeffery Larimer | 1 | 5 | 1947-1947 |
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