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| First Basemen Single-Season Runs Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Runs | PA | Year | Career Leaderboard |
| 1. | Sean Hawk | 139 | 689 | 1949 | |
| 2. | Sean Hawk | 136 | 693 | 1948 | |
| 3. | Alonzo Zendejas | 120 | 703 | 1950 | |
| 4. | Sean Hawk | 118 | 673 | 1947 | |
| 5. | Leon Rebello | 113 | 673 | 1948 | |
| 6. | Leon Rebello | 111 | 689 | 1949 | |
| 7. | Todd Ryerson | 108 | 682 | 1948 | |
| 8. | Russell Christman | 106 | 703 | 1947 | |
| 9. | Sean Hawk | 104 | 584 | 1950 | |
| Russell Christman | 104 | 699 | 1948 | ||
| 11. | Rupert McKown | 102 | 679 | 1949 | |
| Todd Ryerson | 102 | 669 | 1947 | ||
| 13. | Daniel Armstead | 100 | 660 | 1950 | |
| Todd Ryerson | 100 | 587 | 1949 | ||
| Daniel Armstead | 100 | 649 | 1948 | ||
| Alonzo Zendejas | 100 | 674 | 1947 | ||
| 17. | Allan Dickerson | 99 | 644 | 1949 | |
| Trevor Maury | 99 | 671 | 1947 | ||
| Seth Uribe | 99 | 644 | 1947 | ||
| 20. | Russell Christman | 98 | 673 | 1950 | |
| Todd Ryerson | 98 | 653 | 1950 | ||
| 22. | Leon Rebello | 94 | 670 | 1947 | |
| 23. | Daniel Tague | 93 | 690 | 1950 | |
| Alonzo Zendejas | 93 | 658 | 1949 | ||
| 25. | Joel Oliveira | 92 | 635 | 1947 | |
| 26. | Trevor Maury | 89 | 641 | 1948 | |
| 27. | Joel Oliveira | 88 | 460 | 1949 | |
| Alonzo Zendejas | 88 | 678 | 1948 | ||
| William Barnwell | 88 | 642 | 1948 | ||
| 30. | Daniel Tague | 87 | 647 | 1949 | |
| 31. | Leon Rebello | 86 | 666 | 1950 | |
| 32. | Howard Goldston | 84 | 604 | 1950 | |
| Russell Christman | 84 | 551 | 1949 | ||
| 34. | Bill Marquardt | 83 | 623 | 1948 | |
| Daniel Armstead | 83 | 679 | 1947 | ||
| 36. | Rupert McKown | 82 | 672 | 1948 | |
| Allan Dickerson | 82 | 630 | 1947 | ||
| 38. | Joel Oliveira | 81 | 688 | 1948 | |
| 39. | Rupert McKown | 78 | 644 | 1950 | |
| 40. | Daniel Armstead | 76 | 633 | 1949 | |
| 41. | Howard Goldston | 75 | 525 | 1949 | |
| Joseph White | 75 | 550 | 1947 | ||
| 43. | Jack Lieberman | 72 | 649 | 1950 | |
| Neil Williams | 72 | 738 | 1948 | ||
| 45. | Daniel Wilson | 71 | 515 | 1947 | |
| 46. | Bill Marquardt | 70 | 606 | 1949 | |
| 47. | Joel Oliveira | 69 | 487 | 1950 | |
| William Barnwell | 69 | 630 | 1949 | ||
| Seth Uribe | 69 | 486 | 1948 | ||
| 50. | Bill Marquardt | 67 | 587 | 1947 | |
| 51. | Neil Williams | 65 | 691 | 1949 | |
| 52. | Allan Dickerson | 64 | 627 | 1950 | |
| 53. | Howard Goldston | 62 | 561 | 1948 | |
| 54. | Seth Uribe | 61 | 351 | 1950 | |
| 55. | Jack Lieberman | 60 | 605 | 1949 | |
| Daniel Tague | 60 | 561 | 1948 | ||
| 57. | Rupert McKown | 59 | 569 | 1947 | |
| 58. | William Barnwell | 58 | 583 | 1950 | |
| 59. | Allan Dickerson | 57 | 617 | 1948 | |
| 60. | David Boyer | 53 | 599 | 1950 | |
| 61. | Kenneth Schultz | 52 | 309 | 1947 | |
| 62. | Donald Bobbitt | 50 | 446 | 1950 | |
| Trevor Maury | 50 | 342 | 1949 | ||
| 64. | Howard Goldston | 49 | 439 | 1947 | |
| 65. | Seth Uribe | 48 | 352 | 1949 | |
| 66. | Daniel Tague | 43 | 288 | 1947 | |
| 67. | Jeremy Bosworth | 41 | 302 | 1949 | |
| 68. | Jeremy Bosworth | 40 | 286 | 1948 | |
| 69. | Bill Marquardt | 39 | 367 | 1950 | |
| Zacarias Morales | 39 | 567 | 1949 | ||
| Joseph White | 39 | 366 | 1948 | ||
| 72. | Edward Leahy | 36 | 420 | 1950 | |
| Kenneth Schultz | 36 | 337 | 1948 | ||
| 74. | David Boyer | 35 | 326 | 1949 | |
| Kenneth Schultz | 35 | 294 | 1949 | ||
| 76. | Trevor Maury | 34 | 307 | 1950 | |
| Jeremy Bosworth | 34 | 256 | 1947 | ||
| 78. | William Barnwell | 31 | 342 | 1947 | |
| 79. | Neil Williams | 27 | 326 | 1947 | |
| 80. | Jeremy Bosworth | 25 | 243 | 1950 | |
| Bill Wright | 25 | 292 | 1947 | ||
| 82. | Jack Lieberman | 24 | 281 | 1948 | |
| 83. | Marcos Colmenares | 22 | 133 | 1950 | |
| Donald Bobbitt | 22 | 152 | 1949 | ||
| 85. | James Wynn | 21 | 198 | 1950 | |
| 86. | Marcos Colmenares | 20 | 161 | 1949 | |
| 87. | Donald Bobbitt | 19 | 143 | 1947 | |
| 88. | Scott Higley | 18 | 137 | 1950 | |
| 89. | David Boyer | 17 | 168 | 1948 | |
| 90. | Edward Leahy | 16 | 146 | 1949 | |
| Marlin Decker | 16 | 95 | 1947 | ||
| 92. | Donald Bobbitt | 14 | 144 | 1948 | |
| 93. | David Boyer | 12 | 168 | 1947 | |
| Marcos Colmenares | 12 | 122 | 1947 | ||
| 95. | Joey Tirado | 11 | 128 | 1950 | |
| 96. | Joseph White | 10 | 115 | 1949 | |
| Morris Feltner | 10 | 114 | 1948 | ||
| John Parker | 10 | 128 | 1947 | ||
| 99. | John Alejos | 9 | 87 | 1947 | |
| 100. | James Wynn | 8 | 107 | 1949 |
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